How does the ketogenic diet induce anti-seizure effects?

Published: 16 Jul 2020
Views: 4531

Click the link below to read a research paper on ScienceDirect, discussing how the ketogenic diet can be utilised to induce anti-seizure effects for patients of epilepsy.


Here are some highlights:

 

Clinical and experimental interest in the ketogenic diet has grown rapidly over the past decade.

Ketone bodies have been linked to inhibitory neurotransmitter release and activation of ATP-sensitive potassium channels.

The ketogenic diet enhances overall cellular bioenergetics and reduces oxidative stress.

Glycolytic diversion and/or restriction may play an important role in the clinical activity of the ketogenic diet.

Modulation of tricarboxylic acid cycle flux may also underlie ketogenic diet effects.

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