The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments
Published: 27 Apr 2021
Results: The ketogenic diet increased dorsal hippocampal oxygen levels, ameliorated postictal hypoxia, and prevented postictal learning impairments. Acute BHB administration did not alter oxygen levels before or after seizures.
Interpretation: The ketogenic diet raised brain oxygen levels and attenuated severe postictal hypoxia likely through a mechanism independent of ketosis and shows promise as a non-pharmacological treatment to prevent the postictal state.
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